The ARC Procedure: An Innovative Non-Touch Technique to Obtain an Endometrial Biopsy

This paper describes the first recorded practice of a full non touch vaginoscopy in diagnostic and blind endometrial biopsy.


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Induction of Labor and Termination of the Previable Pregnancy

Medgyn Bierer and Sopher Forceps and Laminaria pictured in article.


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Overview of second-trimester pregnancy termination

Medgyn Bierer and Sopher Forceps and Laminaria pictured in article.


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The effect of endometrial injury on first cycle IVF/ICSI outcome: A randomized controlled trial

This study was to evaluate the effect of endometrial injury induced in preceding cycle on IVF outcome. MedGyn Endosampler was used for endometrial sampling.


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Prokineticin 1 and leukemia inhibitory factor mRNA expression in the endometrium of women with idiopathic recurrent pregnancy loss

MedGyn Endosampler was used to determine the expression patterns of prokineticin 1 (PROK1) and leukemia inhibitory factor (LIF) in normal fertile women with idiopathic recurrent pregnancy loss (RPL).


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A randomised trial of Medgyn Endosampler® vs Endocurette® in an outpatient hysteroscopy clinic setting

With the increase use of Endometrial biopsy devices like Medgyn’s Endosampler, this study was performed on random trail in a outpatient clinic. The study found Medgyn’s Endosampler to obtain substantially lower insertion rates compared to other sampling devices, which positively reflects the efficiency of Medgyn’s Endosampler.


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Metalloestrogen cadmium stimulates proliferation of stromal cells derived from the eutopic endometrium of women with endometriosis.

A study found that at 48 hours, Cd-induced endometrial stromal cell proliferation was higher in women with endometriosis than in women without endometriosis.


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Detection of two biological markers of intercourse: prostate-specific antigen and Y-chromosomal DNA.

A Johns Hopkins School of Medicine study used the MedGyn Intrauterine Catheter in aiming to detect biological markers of intercourse. Read the article


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Microvascular Density as a Parameter of Endometrial Assessment in Infertile Women

A study estimated the cut-off of microvascular density determinative of good endometrial receptivity that can predict the fertility of the patient and be used as a prognostic marker in infertile patients, particularly in developing countries.


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Efficacy, safety, acceptability and affordability of cryotherapy: a review of current literature.

A study in the Journal of Reproductive Medicine reviewed current literature addressing the technique, efficacy, safety and acceptability of cryotherapy. The review found cryotherapy to be very affordable and feasible to integrate into cervical cancer screening and treatment programs.


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WHO technical specifications Cryosurgical equipment for the treatment of precancerous cervical lesions and prevention of cervical cancer

MedGyn participated in meeting with WHO, UNFPA, PATH and clinical experts to dicuss clinical recommendations in the use of cryosurgery for cervical cancer prevention.


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Role of CD56 and CD57 uterine natural killer cells and E-cadherin in either successful implantation or recurrent abortion

A study published in the Egyptian Journal of Pathology investigated the role of uterine natural killer cells and E-cadherin in human endometrium of nonpregnant women and of those with recurrent abortion to find out their role in implantation or recurrent abortion.


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Endometrial sampling: a comparison between the Pipelle® endometrial sampler and the Endosampler®

A study comparing the adequacy of endometrial sampling by the Endosampler® and the Pipelle® showed that the Endosampler® collected more endometrium than the Pipelle®. This may well translate into a higher adequacy of specimen obtained by the Endosampler®.


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Performance of cryotherapy devices using nitrous oxide and carbon dioxide.

A study comparing four cryotherapy devices found that the MedGyn Cryotherapy System achieved temperatures below –50 °C regardless of whether N2O, medical-grade CO2, or industrial-grade CO2 was used, while the performance of some other cryotherapy devices was suboptimal.


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Laminaria tent vs misoprostol for cervical priming before hysteroscopy: Randomized study.

In a study published in the Journal of Minimally Invasive Gynecology, women who received laminaria tents as opposed to misoprostol for cervical priming before operative hysteroscopy were less likely to need cervical dilation and suffered fewer adverse effects.


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Diagnosis of endometriosis by detection of nerve fibres in an endometrial biopsy: a double blind study

An Australian study found that endometrial biopsy, with detection of nerve fibers, provided a reliability of diagnosis of endometriosis close to the accuracy of laparoscopic assessment by experienced gynecological laparoscopists.


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Pathologically Increased Endometrial Thickness in Ultrasound Examination: Causes, Diagnosis and Treatment

One of many articles showing the MedGyn Endosampler used for endometrial biopsy in this study.


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Endometrial Gene Expression in Early Pregnancy: Lessons From Human Ectopic Pregnancy

The study found that the ectopic embryo has a significant impact, by an endocrine mechanism, on the endometrium when compared with the window of implantation.


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A pilot study to evaluate the relative efficacy of endometrial biopsy and full curettage in making a diagnosis of endometriosis by the detection of endometrial nerve fibers.

Article on MedGyn Endosampler which was used in a study to detect endometriosis based on nerve fibers.


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Cervical priming prior to operative hysteroscopy: a randomized comparison of laminaria versus misoprostol

Egyptian study on using laminaria before hysteroscopy. The study demonstrates cervical dilation as good as misoprostol.


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An evaluation of manual vacuum aspiration instruments

Article on manual vacuation stating Medgyn superior features to competitors and experience of administrators and clinicians should enable them to determine which MVA is best for their environment.


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Which cannulae fit the Ipas™ manual vacuum aspiration syringe?

Study showing the MedGyn Flexible Curette as a good fit for the Ipas as it was able to maintain pressure without any leaks.


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Cannula fracture in first trimester abortion: a case report and survey of NAF providers.

A survey of National Abortion Federation members found that cannula resterilization did not significantly increase the likelihood of a fracture during a first trimester abortion


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Second trimester abortion by laminaria followed by vaginal misoprostol or intrauterine prostaglandin F2alpha: a randomized trial.

Laminaria study using the Medgyn Laminaria which states misoprostol works well after laminaria begins cervical dilation.

Cervical dilation from laminaria tents and synthetic osmotic dilators used for 6 hours before abortion.

A study comparing thick laminaria tents with two synthetic osmotic devices for softening and dilating the cervix before abortions found that all the decides provided safe cervical dilation and softening, but thick tents were most effective.


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Laminaria versus Dilapan osmotic cervical dilators for outpatient dilation and evacuation abortion: randomized cohort comparison of 1001 patients

Study found both osmotic dilators are acceptable for use in overnight dilation in this procedure, but the Dilapan dilator is more likely to disintegrate, retract, or present minor problems associated with poor dilation.


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The Cell-Sweep. A new cervical cytology sampling device.

A study comparing the Cell-Sweep and the Cytobrush and Ayre spatula found that though the proportion of smears lacking endocervical cells was statistically greater with the Cell-Sweep than with the Cytobrush/Ayre spatula, there was no difference in the rate of detection of atypical squamous cells and low grade SIL. The Cell-Sweep appeared to detect an increased number of high grade SILs.


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